It is a recombinant replication defective adenovirus type 5 vector ad5 expressing the recombinant spike protein of sars cov 2 it was prepared by cloning an optimized full length gene of the s protein along with the plasminogen activator signal peptide gene in the ad5 vector devoid of e1 and e3 genes. Reverse genetics technologies to generate recombinant influenza viruses with defined genetic sequences from plasmid dna were introduced in 1990 ref 158 these techniques should improve both . An essential role of open access is the long term preservation of peer reviewed scholarly journal articles and research data open access is not only used for journal articles but is also being implemented to theses scholarly monographs and book chapters promotion of open access is very crucial to encourage innovation socio economic development and flow of knowledge around the world as . Virology 3 semester 2 smbb 2503 the course is designed for student in order to be able to distinguish between viruses and other organisms based on its identification disease caused and life cycle replication of different type of viruses will be discussed students will also be taught on the impact of viral infections towards society